Browse all practice questions for the Glucose Management Practice Test. Search by topic, open any question and review its full explanation, then test yourself in the practice quiz.

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  • What is the recommended approach to starting metformin in patients with reduced kidney function?
  • Which of the following interactions increases the risk of hypoglycemia when taking sulfonylureas?
  • What are the typical glucose targets during pregnancy for a patient with diabetes?
  • Which is a component of DKA treatment?
  • What is the initial insulin infusion rate after fluids are started?
  • Which item best represents a core component of a hospital glucose management protocol?
  • Which site provides the most consistent absorption for insulin?
  • What is the primary mechanism of action of DPP-4 inhibitors?
  • Why are SGLT2 inhibitors associated with euglycemic diabetic ketoacidosis?
  • What is the mechanism of action of alpha-glucosidase inhibitors?
  • Which mechanism reduces hepatic glucose production?
  • Meglitinides are shorter acting than sulfonylureas.
  • Which drugs are DPP-4 inhibitors?
  • Which of the following is a GLP-1 receptor agonist used for type 2 diabetes and weight loss?
  • In DKA management, when the potassium level is 3.3–5.0 mEq/L, what is recommended?
  • Which of the following is a typical appearance of intermediate-acting insulin?
  • How does pregnancy affect insulin requirements?
  • Which drug is primarily eliminated by the liver?
  • The OGTT criterion for diabetes is a 2-hour plasma glucose greater than 200 mg/dL.
  • How should exercise be managed for a person with type 1 diabetes on insulin therapy?
  • A1c goal for most diabetes patients is
  • Why is interstitial CGM measurement lagged, and how should this affect treatment decisions?
  • Which agents are described as new GLP-1 receptor agonists for type 2 diabetes or weight loss?
  • The major cause of complications and death in diabetes is due to which type of vascular damage?
  • Long-acting insulin is primarily used for basal control. Which option reflects this use most accurately?
  • During a sick day for type 1 diabetes when meals cannot be tolerated, what is the recommended insulin approach?
  • Which statement about GLP-1 receptor agonists is NOT supported by the material?
  • What is the typical preprandial plasma glucose target for most nonpregnant adults with diabetes?
  • How often should A1c be checked in diabetes management?
  • Alpha-glucosidase inhibitors can decrease the absorption of which nutrient?
  • Which fasting glucose range defines prediabetes?
  • What are potential adverse effects of DPP-4 inhibitors?
  • An A1c of 5.9% indicates prediabetes.
  • Which criterion is used in the oral glucose tolerance test for diagnosing diabetes?
  • What are common triggers for DKA in patients with type 1 diabetes?
  • Which features distinguish hyperosmolar hyperglycemic state (HHS) from diabetic ketoacidosis?
  • Which approach helps distinguish postprandial hyperglycemia from fasting hyperglycemia when adjusting therapy?
  • What is the purpose of corrections around meals in postprandial management?
  • When is the best time to take a sulfonylurea?
  • In a multiple daily injections regimen, what is the primary role of basal insulin versus prandial insulin?
  • Which drug is a meglitinide?
  • Which option lists a GLP-1 receptor agonist?
  • Which of the following are common insulin-related complications?
  • Which statement best describes the sequence of therapy for type 2 diabetes as described here?
  • How are alpha-glucosidase inhibitors administered?
  • Which drug is a DPP-4 inhibitor?
  • What is the general in-hospital glucose target range for non-critically ill patients?
  • How often should blood glucose be checked after starting IV insulin in DKA?
  • Which of the following is a long-acting insulin analog?
  • First-line pharmacotherapy for type 2 diabetes is
  • What is the primary mechanism of action of thiazolidinediones?
  • Colesevelam is which type of lipid-lowering agent?
  • MOA of amylin mimetics like pramlintide?
  • Which statement about CGM accuracy is true regarding MARD?
  • Duration of fast-acting insulin?
  • In pediatric patients, what is the most common complication in diabetes?
  • Which metformin formulation is dosed twice daily with meals?
  • Peak and duration of regular insulin?
  • Which insulin is not rapid-acting?
  • Which is a common adverse effect of sulfonylureas?
  • Which sites are listed for subcutaneous insulin administration?
  • What strategy helps mitigate hyperglycemia risk when steroids are used in a patient with diabetes?
  • What is the correction factor per 1 unit insulin according to the 1800-rule?
  • Where is insulin produced?
  • Which of the following is a symptom of hypoglycemia?
  • What is the typical starting dose and monitoring for a patient on continuous insulin infusion in DKA?
  • Which order is correct when administering intermediate and regular insulin together?
  • What is added after metformin failure in the described plan?
  • What is the first-line fluid in diabetic ketoacidosis and how is it administered?
  • In DKA, when should insulin be withheld due to potassium level, and when should potassium be replaced?
  • What is recommended if metformin fails or is contraindicated?
  • Which are common adverse effects of metformin?
  • What defines euglycemic diabetic ketoacidosis (DKA)?
  • Repaglinide peak concentration occurs approximately after how long?
  • How is the anion gap calculated, and what does elevated gap indicate in DKA?
  • Which class of drugs reduces insulin resistance?
  • Which insulin type is typically cloudy in appearance?
  • What is the typical administration frequency of intermediate insulin for glycemic control?
  • Which of the following is a GLP-1 receptor agonist?
  • Which injection site is associated with the slowest absorption for insulin?
  • Which mechanism mimics incretin hormones?
  • Which of the following represents main categories of antidiabetic medications that do not directly modify insulin therapy?
  • When to take regular insulin?
  • Which sign is commonly observed in diabetic ketoacidosis?
  • Metformin can decrease absorption of which vitamins?
  • In DKA management with IV insulin, how often should blood glucose be checked?
  • Regular insulin MOA?
  • When is a switch to a basal-bolus regimen appropriate for type 2 diabetes?
  • Pre-diabetes is an ______.
  • Which pump-related issue can manifest as signs of impending pump failure?
  • When is fast-acting glucose taken?
  • Which of the following is a common symptom of hypoglycemia that prompts immediate treatment?
  • Can long-acting insulin be mixed with other forms in the same syringe?
  • In diabetic ketoacidosis, bicarbonate therapy is recommended under what condition?
  • During illness, what is the purpose of continuing basal insulin in type 1 diabetes?
  • Which storage condition helps insulin stability?
  • How do you correct sodium for hyperglycemia in DKA/HHS?
  • What is a common injection-site complication of insulin therapy?
  • Which of the following is NOT a DPP-4 inhibitor?
  • What effect do nonselective beta-blockers have on hypoglycemia recognition?
  • Which of the following is NOT a listed long-acting insulin analog?
  • In DKA fluid therapy, when is it appropriate to switch from 0.9% NaCl to 0.45% NaCl?
  • DKA signs beyond hyperglycemia?
  • Which mechanism is described as improving insulin sensitivity?
  • What is the mechanism of action of meglitinides (glinides)?
  • Which statement best describes the rationale for hydration during sick day management?
  • A1c range defines prediabetes?
  • Sulfonylureas should be avoided in which situation?
  • What are some critical components of a comprehensive glucose management plan for hospitalized patients?
  • Bromocriptine is classified as which type of medication?
  • Pramlintide is an amylin mimetic used with insulin in which diabetes types?
  • Sulfonylurea MOA?
  • HHS occurs more commonly in which type of diabetes?
  • Fast-acting insulin formulations are?
  • Which mechanism delays carbohydrate absorption?
  • How does glucagon work in severe hypoglycemia, and what follow-up steps are needed?
  • What does the MARD value indicate in CGM readings?
  • Which of the following is a sign of impending insulin pump failure?
  • Why is rapid-acting insulin preferred for correcting hyperglycemia?
  • DPP-4 inhibitors have no relevant drug-drug interactions or contraindications.
  • Which of the following describes common adverse effects of alpha-glucosidase inhibitors?
  • What is the recommended monitoring for lipolysis and ketone production in DKA?
  • How should severe hypoglycemia with impaired consciousness be treated?
  • Which mechanism replaces insulin?
  • Which insulin type is used with the 1800-rule correction factor?
  • Which is a mechanism of action of metformin?
  • In DKA management, bicarbonate therapy is not routinely recommended unless the pH is below which threshold?
  • Which statement about postprandial glucose and A1C is correct?
  • SGLT-2 inhibitors work by increasing urinary glucose excretion.
  • How does dehydration affect glucose concentration readings and management?
  • Common adverse effects of SGLT-2 inhibitors include genital fungal infections and increased urination.
  • Which statement best describes the dehydration aspect of diabetic ketoacidosis?
  • Opened insulin lasts for how long?
  • What is the first-line agent in the described type 2 diabetes treatment plan?
  • What is the mechanism of GLP-1 receptor agonists?
  • Which mechanism increases glucose secretion in urine?
  • Which CGM metric is best used to assess time within target range, and what is a typical target?
  • What is a fatal consequence of hypoglycemia?
  • Which adverse event is listed for new GLP-1 receptor agonists?
  • What is the typical route for administering long-acting insulin?
  • How is euglycemic diabetic ketoacidosis defined?
  • Which statement best describes the administration timing of repaglinide?
  • In the management of Hyperosmolar Hyperglycemic State, what is the role of hydration status and initial fluid choice?
  • Which of the following items are common presenting features of diabetic ketoacidosis?
  • In DKA, fluid management as glucose falls?
  • Amylin mimetics have what impact on the absorption of oral medications?
  • What is the typical A1C goal for many adults with diabetes?
  • Which of the following is an SGLT-2 inhibitor?
  • Which statement about DPP-4 inhibitors is true?
  • Which factor is used to guide insulin-to-carbohydrate ratio (ICR) adjustment after the initial 500-rule estimate?
  • Lipohypertrophy is most likely caused by which practice?
  • Which statement about meglitinides is true?
  • Which insulin is a short-acting/regular insulin?
  • How should clinicians use CGM data when readings are abnormal?
  • Which substances interact with metformin?
  • To manage postprandial hyperglycemia in type 2 diabetes with standard basal insulin, which approach is recommended?
  • The glucose management goal in diabetes care is
  • Nateglinide peak occurs around how many minutes after dosing?
  • Exenatide is a GLP-1 receptor agonist.
  • DPP-4 inhibitors have a dual effect on insulin and glucagon release. Which description is correct?
  • Which drug is an amylin mimetic that complements insulin?
  • Which scenarios are commonly associated with euglycemic DKA?
  • If potassium is normal or high and hyperglycemia persists after initial fluids in DKA, what is the recommended step?
  • The statement 'In Hyperosmolar Hyperglycemic State, there is little to no change in blood pH or ketoacid levels' is true or false?
  • DPP-4 inhibitors are commonly referred to by which suffix?
  • Which condition increases the risk of developing euglycemic DKA in patients taking SGLT2 inhibitors?
  • Are alpha-glucosidase inhibitors approved only for type 2 diabetes mellitus?
  • Which of the following are drug interactions with canagliflozin?
  • Which of the following is NOT a route for regular insulin formulations?
  • What does the term ICR stand for in insulin therapy?
  • If a CGM shows a rapid decline into hypoglycemia and the patient is symptomatic, what is the recommended action?
  • Where should unopened insulin be stored?
  • Which drugs are sulfonylureas?
  • Which statement about metformin and hypoglycemia is correct?
  • The Dawn phenomenon is best described as early morning hyperglycemia due to dawn hormones. What is a common management approach?
  • Which agent is a dual GIP and GLP-1 receptor agonist?
  • Repaglinide is primarily eliminated by which organ?
  • Which test reflects average blood glucose over roughly three months?
  • Which insulin is categorized as intermediate-acting?
  • What is glycemic variability and why is it clinically important?
  • Adjustments for glycemic targets in older adults?
  • Which statement best describes the relationship between postprandial glucose and A1C?
  • Using the 500-rule, how is the insulin-to-carbohydrate ratio (ICR) derived?
  • To address postprandial hyperglycemia in type 2 diabetes when using basal insulin, which adjustment is commonly considered?
  • In DKA management, when should dextrose be added to IV fluids?
  • Which statement is true about drawing regular insulin with intermediate insulin?
  • What factors increase insulin requirements during an acute illness?
  • Which DPP-4 inhibitor is listed with the brand name Januvia?
  • When should you switch to dextrose-containing fluids during DKA treatment?
  • At what point should you switch to dextrose-containing fluids in DKA management?
  • Do alpha-glucosidase inhibitors carry a risk of hypoglycemia when used as monotherapy?
  • A fasting glucose greater than 126 mg/dL is diagnostic for diabetes.
  • Which adverse effect is associated with thiazolidinedione therapy?
  • Which adverse effect is associated with amylin mimetics?
  • Do sulfonylureas cause hypoglycemia?
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